Vitamin B15(Synonyms: 潘氨酸; Pangamic Acid)

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Vitamin B15 (Synonyms: 潘氨酸; Pangamic Acid)

Vitamin B15 (Pangamic Acid) 是一种天然的,植物种子中广泛存在的物质,可以用作刺激细胞呼吸的物质。Vitamin B15 含有 D-葡萄糖基二甲基氨基乙酸。Vitamin B15 也是一种免疫校正剂。Vitamin B15 可用于多种疾病的研究。

Vitamin B15(Synonyms: 潘氨酸; Pangamic Acid)

Vitamin B15 Chemical Structure

CAS No. : 20858-86-0

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Vitamin B15 (Pangamic Acid) is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 contains D-gluconodimethyl amino acetic acid. Vitamin B15 is also a immune-correcting agent[1][2]. Vitamin B15 can be used for wide range of diseases.

体外研究
(In Vitro)

Unequivocal reports on identity and functions of Vitamin B15 (Pangamic Acid) in the literature make it impossible, however, to accurately assess either its chemical identity or its biological or medical functions. Indeed, the chemical identity of genuine Vitamin B15 (Pangamic Acid) has apparently never been ascertained or verifiably chemically identified as being the molecular weight 281-ester of DMG and gluconic acid claimed by Krebs and some Russian authors, and there is considerable doubt that such a stable substance exists with the straight chain sugar gluconic acid. Vitamin B15 (Pangamic Acid) is identified as a substance most likely containing both a sugar and a dimethylamine group[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Addition of Vitamin B15 (Pangamic Acid) to the diet (Wistar rats; 2.5 mg/100 g of diet) increases the degree of fatty infiltration of the liver which is maintained at a stable level throughout the whole experiment, i.e. 12-18 months[1][3].
Vitamin B15 (Pangamic Acid) enriches in the rat diet reduced glutathione peroxidase (after one year) and also glutathione transferase (after 18 months) in the brains of the animals, thus impairing their antioxidative capacities[1].
Vitamin B15 (Pangamic Acid) treatment increase the cytochrome oxidase- and also succinate dehydrogenase-activity in certain rat tissues[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

281.26

Formula

C10H19NO8

CAS 号

20858-86-0

中文名称

潘氨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
In Vitro: 

H2O : 250 mg/mL (888.86 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.5554 mL 17.7771 mL 35.5543 mL
5 mM 0.7111 mL 3.5554 mL 7.1109 mL
10 mM 0.3555 mL 1.7777 mL 3.5554 mL

参考文献
  • [1]. Schneider D, et al. Studies on the chemical identity and biological functions of pangamic acid. Arzneimittelforschung. 1999 Apr;49(4):335-43.

    [2]. Zemskov AM, et al. Typical immune system responses to differential monotherapy with immune-correcting drugs. Fiziol Cheloveka. 2001 Jul-Aug;27(4):97-103.

    [3]. Ziemlański S, et al. Effect of long-term diet enrichment with selenium, vitamin E and vitamin B15 on the degree of fatty infiltration of the liver. Acta Physiol Pol. 1984 Jul-Aug;35(4):382-97.

    [4]. Vitamin B15

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