m-PEG2-acid

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m-PEG2-acid 

m-PEG2-acid 是一种基于PEG 的 PROTAC linker，可用于 PROTAC 的合成。

m-PEG2-acid

m-PEG2-acid Chemical Structure

CAS No. : 149577-05-9

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生物活性

m-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

148.16

Formula

C6H12O4
CAS 号

149577-05-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

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