N-(Azido-PEG3)-N-Boc-PEG4-acid | whatman (沃特曼)

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N-(Azido-PEG3)-N-Boc-PEG4-acid

N-(Azido-PEG3)-N-Boc-PEG4-acid 是一种 PEG 类 PROTAC linker，含有一个叠氮基团，可以用来合成 PROTAC。

N-(Azido-PEG3)-N-Boc-PEG4-acid Chemical Structure

CAS No. : 2112731-95-8

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100 mg		询价
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生物活性

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker with a terminal azide group and is used in the synthesis of PROTACs^[1]

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

566.64

Formula

C₂₄H₄₆N₄O₁₁

CAS 号

2112731-95-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Kanazaki K, et al. Feasibility of poly(ethylene glycol) derivatives as diagnostic drug carriers for tumor imaging. J Control Release. 2016 Mar 28;226:115-23.

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