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Mal-PEG2-Val-Cit-amido-PAB-OH
Mal-PEG2-Val-Cit-amido-PAB-OH 是一种可降解 (cleavable) 的 ADC linker,用于抗体偶联药物 (ADCs) 的合成。 Mal-PEG2-Val-Cit-amido-PAB-OH 也可用作 PROTAC 的 Linker,可用于 PROTAC 的合成。
Mal-PEG2-Val-Cit-amido-PAB-OH Chemical Structure
CAS No. : 2055041-38-6
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250 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-amido-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
618.68 |
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Formula |
C29H42N6O9 |
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CAS 号 |
2055041-38-6 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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