Aminooxy-PEG1-azide

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Aminooxy-PEG1-azide 

Aminooxy-PEG1-azide 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC。

Aminooxy-PEG1-azide

Aminooxy-PEG1-azide Chemical Structure

CAS No. : 2100306-70-3

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生物活性

Aminooxy-PEG1-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

146.15

Formula

C4H10N4O2
CAS 号

2100306-70-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

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