Azido-PEG2-CH2COOH

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Azido-PEG2-CH2COOH 

Azido-PEG2-CH2COOH 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。

Azido-PEG2-CH2COOH

Azido-PEG2-CH2COOH Chemical Structure

CAS No. : 882518-90-3

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生物活性

Azido-PEG2-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

189.17

Formula

C6H11N3O4

CAS 号

882518-90-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Yimin Qian, et al. Composés et procédés pour la dégradation ciblée de protéines contenant un bromodomaine. WO2017030814A1.

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