m-PEG6-Tos

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m-PEG6-Tos 

m-PEG6-Tos 是一种 PROTAC linker，属于 PEG 类。Tos-PEG6-m 可用于合成 PROTAC 分子。

m-PEG6-Tos

m-PEG6-Tos Chemical Structure

CAS No. : 155887-96-0

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生物活性

m-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

450.54

Formula

C20H34O9S
CAS 号

155887-96-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

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