N-Boc-N-bis(PEG2-OH) | whatman (沃特曼)

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N-Boc-N-bis(PEG2-OH)

N-Boc-N-bis(PEG2-OH) 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。N-Boc-N-bis(PEG2-OH) 可用于合成一系列 PROTAC 分子。N-Boc-N-bis(PEG2-OH) 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。

N-Boc-N-bis(PEG2-OH) Chemical Structure

CAS No. : 275385-03-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性

N-Boc-N-bis(PEG2-OH) is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target^[1]

Cleavable

PEGs

Alkyl/ether

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

293.36

Formula

C₁₃H₂₇NO₆

CAS 号

275385-03-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. Deqiang A, et al. Process for preparation of tetramaleimide linker and application. WO2019033773A1.

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