NH2-PEG6-CH2CH2COOH

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NH2-PEG6-CH2CH2COOH 

NH2-PEG6-CH2CH2COOH 是一种可降解 (cleavable) 的 6 单元 PEG 类 ADC linker，用于抗体偶联药物 (ADC) 的合成。NH2-PEG6-CH2CH2COOH 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。

NH2-PEG6-CH2CH2COOH

NH2-PEG6-CH2CH2COOH Chemical Structure

CAS No. : 905954-28-1

规格 价格 是否有货 数量
100 mg ￥1000 In-stock
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生物活性

NH2-PEG6-CH2CH2COOH is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). NH2-PEG6-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Cleavable

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

353.41

Formula

C15H31NO8
CAS 号

905954-28-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Jaume Pons, et al. Engineered polypeptide conjugates and methods for making thereof using transglutaminase. US20130230543A1.

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