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Tetraethylene glycol monotosylate (Synonyms: Tos-PEG4)
Tetraethylene glycol monotosylate 是一种可降解 (cleavable) 的基于酰基腙的 ADC linker，用于合成抗体偶联药物 (ADCs)。Tetraethylene glycol monotosylate 也可用作 PROTAC 的 Linker，可用于 PROTAC 的合成。
Tetraethylene glycol monotosylate Chemical Structure
CAS No. : 77544-60-6
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| 生物活性 |
Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Tetraethylene glycol monotosylate also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
348.41 |
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| Formula |
C15H24O7S |
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| CAS 号 |
77544-60-6 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 参考文献 |
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