m-PEG4-propargyl

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m-PEG4-propargyl 

m-PEG4-propargyl 是一种 PROTAC linker，属于 PEG 类。m-PEG4-Propargyl 可用于合成一系列 PROTAC 分子。

m-PEG4-propargyl

m-PEG4-propargyl Chemical Structure

CAS No. : 1101668-39-6

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生物活性

m-PEG4-propargyl is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

246.30

Formula

C12H22O5
CAS 号

1101668-39-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.

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