Neogambogic acid

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Neogambogic acid 

Neogambogic acid 是藤黄的有效成分,可诱导细胞凋亡并具有抗癌作用。Neogambogic acid 对耐甲氧西林的金黄色葡萄球菌 (MRSA) 具有明显的抑制活性。

Neogambogic acid

Neogambogic acid Chemical Structure

CAS No. : 93772-31-7

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5 mg ¥1190 询问价格 & 货期
10 mg ¥2020 询问价格 & 货期
20 mg ¥3430 询问价格 & 货期

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生物活性

Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2].

体外研究
(In Vitro)

Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Neogambogic acid arrests A549-induced tumor growth in nude mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

646.77

Formula

C38H46O9

CAS 号

93772-31-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wang K, et al. The mechanism of neogambogic acid-induced apoptosis in human MCF-7 cells.Acta Biochim Biophys Sin (Shanghai). 2011 Sep;43(9):698-702.

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