Isodeoxyelephantopin(Synonyms: 异去氧苦地胆苦素)

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Isodeoxyelephantopin (Synonyms: 异去氧苦地胆苦素)

Isodeoxyelephantopin 是一种倍半萜烯内酯,可从Elephantopus scaber 中分离得到。Isodeoxyelephantopin 可诱导活性氧的生成,抑制NF-κB 的激活。Isodeoxyelephantopin 还能调节LncRNA 的表达,有抗乳腺癌的作用。

Isodeoxyelephantopin(Synonyms: 异去氧苦地胆苦素)

Isodeoxyelephantopin Chemical Structure

CAS No. : 38927-54-7

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生物活性

Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer[1][2].

体外研究
(In Vitro)

Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

344.36

Formula

C19H20O6

CAS 号

38927-54-7

中文名称

异去氧苦地胆苦素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Verma SS, et al. Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer. Sci Rep. 2019 Nov 29;9(1):17980.

    [2]. Yunna Kim, et al. Treatment of Hominis placenta pharmacopuncture for a patient with mild neurocognitive disorder: Case report. J Pharmacopuncture. 2019 Dec; 22(4): 279–283.

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