Mal-amido-PEG5-C2-​NHS ester

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Mal-amido-PEG5-C2-​NHS ester 

Mal-amido-PEG10-C2-NHS ester 是包含马来酰亚胺基团和 NHS 酯的,不可降解 (non-cleavable) 的 ADC linker。NHS ester 可用于标记蛋白质,胺修饰的寡核苷酸和其他含胺分子的伯胺 (-NH2)。

Mal-amido-PEG5-C2-​NHS ester

Mal-amido-PEG5-C2-​NHS ester Chemical Structure

CAS No. : 1315355-92-0

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100 mg ¥11490 询问价格 & 货期

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生物活性

Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2]

IC50 & Target

Non-cleavable

 

分子量

557.55

Formula

C24H35N3O12

CAS 号

1315355-92-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145.

    [2]. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A

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