Hellebrigenin(Synonyms: 蟾蜍它里定)

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Hellebrigenin (Synonyms: 蟾蜍它里定)

Hellebrigenin,属于心脏活性类固醇的丁二烯内酯之一,从中药中分离出来。Hellebrigenin 诱导 DNA 损伤和细胞周期 G2/M 阻滞。 Hellebrigenin 触发线粒体介导的细胞凋亡。

Hellebrigenin(Synonyms: 蟾蜍它里定)

Hellebrigenin Chemical Structure

CAS No. : 465-90-7

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生物活性

Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.

分子量

416.51

Formula

C24H32O6

CAS 号

465-90-7

中文名称

蟾蜍它里定

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Deng LJ, et al. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chem Biol Interact. 2014 Aug 5;219:184-94.

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