Ethyl Orsellinate(Synonyms: 山梨酸乙酯)

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Ethyl Orsellinate (Synonyms: 山梨酸乙酯)

Ethyl Orsellinate 是地衣代谢产物,lecanoric acid 的衍生物,具有抗增殖和抗肿瘤活性。Ethyl Orsellinate 抑制 A.salina 的细胞毒性活性,LC50 为 495 μM。

Ethyl Orsellinate(Synonyms: 山梨酸乙酯)

Ethyl Orsellinate Chemical Structure

CAS No. : 2524-37-0

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生物活性

Ethyl orsellinate is a lichen metabolite and a derivative of lecanoric acid with antiproliferative and antitumour activities[1]. Ethyl Orsellinate is against A. salina for the cytotoxic activity with an LC50 of 495 μM[2].

体外研究
(In Vitro)

Ethyl Orsellinate (0-50 μg/ml; 48 hours) inhibits Hep-2 cells, MCF-7 breast cancer cells, and 786-0 kidney carcinoma cells, as well as B16-F10 murine melanoma and non-cancerous Vero cells (IC50s=31.2, 70.3, 47.5, 64.8, and 28.1 µg/ml, respectively)[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

196.20

Formula

C10H12O4

CAS 号

2524-37-0

中文名称

山梨酸乙酯

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Bogo D, et al. In vitro antitumour activity of orsellinates. Z Naturforsch C. 2010 Jan-Feb;65(1-2):43-8.

    [2]. Gomes AT, et al. Cytotoxic activity of orsellinates. Z Naturforsch C. 2006 Sep-Oct;61(9-10):653-7.

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