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Dehydrocorydaline nitrate (Synonyms: 硝酸脱氢紫堇碱; 13-Methylpalmatine nitrate) 纯度: 99.89%
Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) 是一种生物碱。Dehydrocorydaline 调节 Bax,Bcl-2 蛋白表达;激活 caspase-7,caspase-8,并使 PARP 失活。Dehydrocorydaline nitrate 能增强 p38 MAPK 活化,具有抗炎、抗癌等功效。。Dehydrocorydaline nitrate 具有强大的抗疟疾作用,并具低细胞毒性 (细胞生存力> 90%), P. falciparum 3D7 strain (IC50=38 nM)。
Dehydrocorydaline nitrate Chemical Structure
CAS No. : 13005-09-9
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
5 mg | ¥3360 | In-stock | |
10 mg | ¥5710 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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生物活性 |
Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP[1]. Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities.[2]. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain[3]. |
IC50 & Target |
IC50: 38 nM (P. falciparum 3D7 strain)[3] |
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分子量 |
428.44 |
Formula |
C22H24N2O7 |
CAS 号 |
13005-09-9 |
中文名称 |
硝酸脱氢紫堇碱;硝酸去氢紫堇碱;硝酸脱氢紫堇硷;硝酸脱氢延胡索碱;硝酸去氢延胡索碱 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
参考文献 |
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