Bullatine A(Synonyms: 雪上一枝蒿甲素)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Bullatine A (Synonyms: 雪上一枝蒿甲素)

Bullatine A 雪上一枝蒿甲素是乌头属 genus Aconitum 的二萜类生物碱，具有抗风湿，抗炎和抗伤害感受作用。 Bullatine A 是一种有效的 P2X7 拮抗剂，可抑制 ATP 诱导的细胞凋亡和 P2X 受体介导的炎症反应。Bullatine A 能缓解过敏反应。

Bullatine A(Synonyms: 雪上一枝蒿甲素)

Bullatine A Chemical Structure

CAS No. : 1354-84-3

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses[1]. Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed[2].

分子量

343.50

Formula

C22H33NO2
CAS 号

1354-84-3
中文名称

雪上一枝蒿甲素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Li J, et al. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, could attenuate ATP-induced BV-2 microglia death/apoptosis via P2X receptor pathways. Brain Res Bull. 2013 Aug;97:81-5.

    [2]. Huang Q, et al. Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models. J Neuroinflammation. 2016 Aug 30;13(1):214.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务