(R)-10,11-Dehydrocurvularin | whatman (沃特曼)

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(R)-10,11-Dehydrocurvularin

(R)-10,11-Dehydrocurvularin 是从弯孢菌中分离出来的一种次生代谢产物。(R)-10,11-Dehydrocurvularin 对一些癌细胞具有浓度依赖性细胞毒性，平均 IC₅₀ 值为 1.25 µM。

(R)-10,11-Dehydrocurvularin Chemical Structure

CAS No. : 1095588-70-7

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生物活性	(R)-10,11-Dehydrocurvularin is a secondary metabolite isolated from Curvularia sp.. (R)-10,11-Dehydrocurvularin displays concentration-dependent cytotoxicity towards human tumor cell lines with a mean IC₅₀ value of 1.25 µM^[1].
IC₅₀ & Target	Heat shock response^[1] TGF-β signalling pathway^[2]
分子量	290.31
Formula	C₁₆H₁₈O₅
CAS 号	1095588-70-7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Greve H, et al. Apralactone A and a New Stereochemical Class of Curvularins from the Marine-Derived Fungus Curvularia sp. European J Org Chem. 2008;2008(30):10.1002/ejoc.200800522.

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