[Asp371]-Tyrosinase (369-377), human

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[Asp371]-Tyrosinase (369-377), human 

Tyrosinase 369-377, human 是一种来自酪氨酸酶 (tyrosinase) 的 HLA-A2.1 限制性表位多肽，已被应用于开发具有混合疗效的肿瘤靶向疫苗。

[Asp371]-Tyrosinase (369-377), human

[Asp371]-Tyrosinase (369-377), human Chemical Structure

CAS No. : 168650-46-2

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生物活性

Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].

分子量

1031.16

Formula

C42H66N10O16S2
CAS 号

168650-46-2
Sequence

Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val
Sequence Shortening

YMDGTMSQV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47.

    [2]. Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86.

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