HPV16-E711-20 epitope

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HPV16-E711-20 epitope 

HPV16-E711-20 epitope 是 HLA-A*0201 限制性人细胞毒性T淋巴细胞 (CTL) 表位的 HPV16 E7 蛋白，在体外显示了与 HLA-A2 的高亲和力结合。HPV16 CTL 表位可能是开发有效肽基抗肿瘤疫苗的良好候选。

HPV16-E711-20 epitope

HPV16-E711-20 epitope Chemical Structure

CAS No. : 160040-04-0

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生物活性

HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro. HPV16 CTL epitopes may be good candidates for the development of an effective peptide-based antitumor vaccine[1].

分子量

1210.35

Formula

C53H83N11O19S
CAS 号

160040-04-0
Sequence

Tyr-Met-Leu-Asp-Leu-Gln-Pro-Glu-Thr-Thr
Sequence Shortening

YMLDLQPETT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ding Z, et al. Cytolytic activity of the human papillomavirus type 16 E711-20 epitope-specific cytotoxic T lymphocyte is enhanced by heat shock protein 110 in HLA-A*0201 transgenic mice. Clin Vaccine Immunol. 2013 Jul;20(7):1027-33.

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