上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
c-Met-IN-1
c-met-IN-1 (compound 16) 是一种高效选择性的 c-Met 抑制剂,IC50 值为 1.1 nM,具有抗肿瘤活性。
c-Met-IN-1 Chemical Structure
CAS No. : 2084836-84-8
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生物活性 |
c-met-IN-1 (compound 16) is a potent and selective c-Met inhibitor, with IC50 of 1.1 nM, with antitumor activity.[1]. |
IC50 & Target |
IC50: 1.1 nM (c-Met)[1] |
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体外研究 (In Vitro) |
c-met-IN-1 (compound 16) exhibits high selectivity and remarkable cytotoxicity against HT-29, MKN-45 and A549 cells with IC50 values of 0.08 μM, 0.22 μM and 0.07 μM, respectively[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
640.70 |
Formula |
C35H37FN6O5 |
CAS 号 |
2084836-84-8 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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