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Losartan-d3 Carboxylic Acid (Synonyms: 氯沙坦羧酸 d3)
Losartan-d3 Carboxylic Acid 是 Losartan 的氘代物。Losartan 是血管紧张素II受体拮抗剂,与血管紧张素II竞争性结合AT1受体,IC50为20 nM。
![Losartan-d3 Carboxylic Acid Chemical Structure Losartan-d3 Carboxylic Acid(Synonyms: 氯沙坦羧酸 d3)](http://www.fluoroprobe.com/wp-content/uploads/2022/05/hy-17512s1.gif)
Losartan-d3 Carboxylic Acid Chemical Structure
CAS No. : 1189729-40-5
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
Losartan-d3 Carboxylic Acid is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM[1][2]. |
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体外研究 (In Vitro) |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
439.91 |
Formula |
C22H18D3ClN6O2 |
CAS 号 |
1189729-40-5 |
中文名称 |
氯沙坦羧酸 d3 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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