Urea-15N2(Synonyms: Carbamide-15N2; Carbonyldiamide-15N2)

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Urea-15N2 (Synonyms: Carbamide-15N2; Carbonyldiamide-15N2)

Urea-15N2 (Carbamide-15N2) 是 15N 标记的 Urea。Urea是一种强效蛋白质变性剂，作用通过直接和间接机制。 一种有效的润肤剂和角质层分离剂。 用作利尿剂。 血尿素氮 (BUN) 已被用于评估肾功能。 广泛用于肥料中的氮源，是化学工业的重要原料。

Urea-15N2(Synonyms: Carbamide-15N2; Carbonyldiamide-15N2)

Urea-15N2 Chemical Structure

CAS No. : 2067-80-3

规格 价格 是否有货
50 mg ￥1200 询问价格 & 货期
100 mg ￥2000 询问价格 & 货期
250 mg ￥4600 询问价格 & 货期

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生物活性

Urea-15N2 (Carbamide-15N2) is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

62.04

Formula

CH415N2O
CAS 号

2067-80-3
中文名称

尿素 15N2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7.

    [3]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 15;19(11):20392.

    [4]. Wang H, et al. Urea. Subcell Biochem. 2014;73:7-29.

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