Azithromycin-d3(Synonyms: 阿奇霉素 13C-d3)

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Azithromycin-d3 (Synonyms: 阿奇霉素 13C-d3)

Azithromycin-d3 (CP 62993-d3) 是 Azithromycin 的氘代物。Azithromycin (CP-62993) 是一种大环内酯抗生素，常用于细菌感染的研究。

Azithromycin-d3(Synonyms: 阿奇霉素 13C-d3)

Azithromycin-d3 Chemical Structure

CAS No. : 163921-65-1

规格 价格 是否有货 数量
1 mg ￥4300 In-stock
5 mg   询价  
10 mg   询价  

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生物活性

Azithromycin-d3 (CP 62993-d3) is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

752.00

Formula

C38H69D3N2O12
CAS 号

163921-65-1
中文名称

阿奇霉素 13C-d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Menzel M, et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. Oncotarget. 2017 Mar 18.

    [3]. Vandooren J, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. PLoS One. 2017 Apr 3;12(4):e0174853.

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