CDK4-IN-1-d6

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CDK4-IN-1-d6 

CDK4-IN-1-d6 是一种 CDK4-IN-1 氘代物。CDK4-IN-1 (compound 63) 是一种 CDK4 抑制剂 (IC50= 10 nM)。

CDK4-IN-1-d6

CDK4-IN-1-d6 Chemical Structure

规格 价格 是否有货
1 mg ￥4500 询问价格 & 货期
5 mg ￥12500 询问价格 & 货期

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生物活性

CDK4-IN-1-d6 is a deuterium labeled CDK4-IN-1. CDK4-IN-1 (compound 63) is a CDK4 inhibitor (IC50= 10 nM)[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

447.01

Formula

C22H23D6ClN8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Cho YS, Borland M, Brain C, et al. 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J Med Chem. 2010;53(22):7938-7957.

    [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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