Acetildenafil-d8

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Acetildenafil-d8 

Acetildenafil-d8 是 Acetildenafil 的氘代物。Acetildenafil 是 phosphodiesterase 5 (PDE5) 抑制剂 Sildenafil 的衍生物。

Acetildenafil-d8

Acetildenafil-d8 Chemical Structure

CAS No. : 1189944-10-2

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生物活性

Acetildenafil-d8 is the deuterium labeled Acetildenafil. Acetildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor Sildenafil.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

474.63

Formula

C25H26D8N6O3

CAS 号

1189944-10-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

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