Deltamethrin-d5(Synonyms: Decamethrin-d5)

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Deltamethrin-d5 (Synonyms: Decamethrin-d5)

Deltamethrin-d5 (Decamethrin-d5) 是 Deltamethrin 的氘代物。Deltamethrin (Decamethrin),一种神经毒性拟除虫菊酯杀虫剂,可在大鼠中产生可逆性的一系列运动症状,包括后肢僵硬和舞蹈性关节炎。

Deltamethrin-d5(Synonyms: Decamethrin-d5)

Deltamethrin-d5 Chemical Structure

CAS No. : 2140301-99-9

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生物活性

Deltamethrin-d5 (Decamethrin-d5) is the deuterium labeled Deltamethrin. Deltamethrin (Decamethrin), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

510.23

Formula

C22H14D5Br2NO3

CAS 号

2140301-99-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Kavlock R, et al. Toxicity studies with decamethrin, a synthetic pyrethroid insecticide. J Environ Pathol Toxicol. 1979;2(3):751-765.;Ray DE. An EEG investigation of decamethrin-induced choreoathetosis in the rat. Exp Brain Res. 1980;38(2):221-227.

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