Deoxythymidine-5′-triphosphate-13C10,15N2 disodium

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Deoxythymidine-5′-triphosphate-13C10,15N2 disodium 

Deoxythymidine-5′-triphosphate-13C10,15N2 disodium 是一种 13C 和 15N 标记的 Deoxythymidine-5′-triphosphate。Deoxythymidine-5′-triphosphate (dTTP)，一种三磷酸核苷，可用于 DNA 的合成。

Deoxythymidine-5

Deoxythymidine-5′-triphosphate-13C10,15N2 disodium Chemical Structure

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生物活性

Deoxythymidine-5′-triphosphate-13C10,15N2 disodium is the 13C-labeled and 15N-labeled Deoxythymidine-5′-triphosphate. Deoxythymidine-5′-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5′-triphosphate (dTTP) is used in the synthesis of DNA[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

538.05

Formula

13C10H1515N2Na2O14P3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5(2):191-202.

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