Methylmalonic acid-d3(Synonyms: Methylpropanedioic acid-d3; Methylmalonate-d3)

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Methylmalonic acid-d3 (Synonyms: Methylpropanedioic acid-d3; Methylmalonate-d3)

Methylmalonic acid-d3 (Methylpropanedioic acid-d3) 是 Methylmalonic acid 的氘代物。Methylmalonic acid (Methylmalonate) 是癌症患者维生素 B-12 缺乏的指标。

Methylmalonic acid-d3(Synonyms: Methylpropanedioic acid-d3;  Methylmalonate-d3)

Methylmalonic acid-d3 Chemical Structure

CAS No. : 42522-59-8

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生物活性

Methylmalonic acid-d3 (Methylpropanedioic acid-d3) is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

121.11

Formula

C4H3D3O4

CAS 号

42522-59-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843.

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