Ethynyl Estradiol-d4(Synonyms: 17α-Ethynylestradiol-d4; Ethynylestradiol-d4)

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Ethynyl Estradiol-d4 (Synonyms: 17α-Ethynylestradiol-d4; Ethynylestradiol-d4)

Ethynyl Estradiol-d4 (17α-Ethynylestradiol-d4) 是 Ethynyl Estradiol 的氘代物。Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) 是生物活性雌激素。

Ethynyl Estradiol-d4(Synonyms: 17α-Ethynylestradiol-d4; Ethynylestradiol-d4)

Ethynyl Estradiol-d4 Chemical Structure

CAS No. : 350820-06-3

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生物活性

Ethynyl Estradiol-d4 (17α-Ethynylestradiol-d4) is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

300.43

Formula

C20H20D4O2
CAS 号

350820-06-3
中文名称

乙炔基雌二醇 d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Djerassi C. Chemical birth of the pill. 1992. Am J Obstet Gynecol. 2006 Jan;194(1):290-8.

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