Tesetaxel(Synonyms: DJ-927)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Tesetaxel (Synonyms: DJ-927)

Tesetaxel是一种口服活性、半合成的紫杉烷类微管抑制剂，用于治疗癌症，包括结肠直肠癌和胃癌。

Tesetaxel(Synonyms: DJ-927)

Tesetaxel Chemical Structure

CAS No. : 333754-36-2

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生物活性

Tesetaxel is a orally active, semisynthetic microtubule inhibitor of the taxane class for the treatment of cancer, including colorectal and gastric cancer.

分子量

881.98

Formula

C46H60FN3O13
CAS 号

333754-36-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Shionoya M, Jimbo T, Kitagawa M, Soga T, Tohgo A. DJ-927, a novel oral taxane, overcomes P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Cancer Sci. 2003;94(5):459-466.

    [2]. Saif MW, Sarantopoulos J, Patnaik A, Tolcher AW, Takimoto C, Beeram M. Tesetaxel, a new oral taxane, in combination with capecitabine: a phase I, dose-escalation study in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011;68(6):1565-1573.

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