PD-1/PD-L1-IN 5

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PD-1/PD-L1-IN 5 

PD-1/PD-L1-IN 5 是一种有效的 PD-1/PD-L1 蛋白/蛋白相互作用抑制剂，IC50 ≤100 nM。详细信息请参考专利文献 WO2017222976A1 中的化合物 Example 1。

PD-1/PD-L1-IN 5

PD-1/PD-L1-IN 5 Chemical Structure

CAS No. : 2170209-51-3

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生物活性

PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].

IC50 & Target

IC50: ≤100 nM (PD-1/PD-L1)[1]
体外研究
(In Vitro)

The compounds modulate PD-1/PD-L1 protein/protein interaction and are useful in the treatment of various diseases including infectious diseases and cancer. The compounds can be used as immunomodulators[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

418.47

Formula

C22H18N4O3S
CAS 号

2170209-51-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.

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