(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride(Synonyms: VH032 phenol-alkylC6-amine dihydrochloride)

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(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride (Synonyms: VH032 phenol-alkylC6-amine dihydrochloride)

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride 是一种合成的 E3 连接酶配体连接缀合物，包含基于 VH032 的 VHL 配体和 PROTAC 降解用的 linker。

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride(Synonyms: VH032 phenol-alkylC6-amine dihydrochloride)

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride Chemical Structure

CAS No. : 2376990-28-0

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生物活性

(S,R,S)-AHPC-phenol-alkylC6-amine dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and an alkyl linker used for PROTAC degrader[1].

分子量

660.70

Formula

C30H47Cl2N5O5S
CAS 号

2376990-28-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.

    [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

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