Seco-Duocarmycin TM

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Seco-Duocarmycin TM 

Seco-Duocarmycin TM 是 Duocarmycins 家族的一种 DNA 烷化剂，可抑制 DNA 合成。Seco-Duocarmycin TM 是一种细胞毒性剂，用作抗体偶联药物中的细胞毒性成分。

Seco-Duocarmycin TM

Seco-Duocarmycin TM Chemical Structure

CAS No. : 236102-87-7

规格 价格 是否有货
25 mg ￥41380 询问价格 & 货期
100 mg ￥137930 询问价格 & 货期

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生物活性

Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC)[1].

IC50 & Target

Duocarmycins

 

分子量

448.47

Formula

C25H24N2O6
CAS 号

236102-87-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Gieseg MA, et al. Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA. Anticancer Drug Des. 1999 Feb;14(1):77-84.

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