Thalidomide-NH-C6-NH2 | whatman (沃特曼)

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Thalidomide-NH-C6-NH2

Thalidomide-NH-C6-NH2 是一种合成的 E3 连接酶配体 -linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。

Thalidomide-NH-C6-NH2 Chemical Structure

CAS No. : 2093386-50-4

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Thalidomide-NH-C6-NH2 的其他形式现货产品:

Thalidomide-NH-C6-NH2 TFA

生物活性	Thalidomide-NH-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology^[1].
体外研究 (In Vitro)	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	372.42
Formula	C₁₉H₂₄N₄O₄
CAS 号	2093386-50-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

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