VCP-Eribulin

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

VCP-Eribulin 

VCP-Eribulin 由 ADC linker (VCP) 和 Eribulin 偶联而成。Eribulin 是一种独特的微管 (microtubule) 抑制剂，具有抗肿瘤活性。VCP-Eribulin 可用于偶联抗体。

VCP-Eribulin

VCP-Eribulin Chemical Structure

CAS No. : 2130869-17-7

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生物活性

VCP-Eribulin consists the ADCs linker (VCP) and Eribulin[1]. Eribulin is a mechanistically unique microtubule inhibitor for cancer[2]. VCP-Eribulin is an Eribulin-based drug for antibody conjugates[1].

IC50 & Target

Traditional Cytotoxic Agents

 

分子量

1135.34

Formula

C59H86N6O16
CAS 号

2130869-17-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1.

    [2]. Towle MJ, et al. Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions. Cancer Res. 2011 Jan 15;71(2):496-505.

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