FAK inhibitor 2

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FAK inhibitor 2 

FAK inhibitor 2 是一种有效的粘着斑激酶 (FAK) 抑制剂,IC50 值为 0.07 nM,有抗肿瘤和抗血管生成活性。

FAK inhibitor 2

FAK inhibitor 2 Chemical Structure

CAS No. : 2354405-14-2

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生物活性

FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50  of 0.07 nM, with antitumor and anti-angiogenesis activities[1].

IC50 & Target

IC50: 0.07 nM (FAK)[1]

分子量

646.75

Formula

C29H33F3N8O2S2

CAS 号

2354405-14-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Su Y, et al. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities. Eur J Med Chem. 2019 May 18;177:32-46.

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