上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Lisaftoclax (Synonyms: APG-2575; Bcl-2/Bcl-xl inhibitor 1)
Lisaftoclax (compound 6) 是 Bcl-2 和Bcl-xl 的双抑制剂，信息来自专利 WO2018027097A1。Lisaftoclax 对Bcl-2 和Bcl-xl 的IC50 值分别为 2 nM 和 5.9 nM。
Lisaftoclax Chemical Structure
CAS No. : 2180923-05-9
| 规格 | 价格 | 是否有货 | |
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| 5 mg | ￥14700 | 询问价格 & 货期 | |
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| 生物活性 |
Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
Lisaftoclax (compound 6) exhibits IC50 values of 5.5 nM and 6.4 nM in Bcl-2 dependent RS4;11 cells and Bcl-xl dependent Molm13 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| Clinical Trial |
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| 分子量 |
882.42 |
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| Formula |
C45H48ClN7O8S |
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| CAS 号 |
2180923-05-9 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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