MC-Sq-Cit-PAB-Gefitinib

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

MC-Sq-Cit-PAB-Gefitinib 

MC-Sq-Cit-PAB-Gefitinib 是抗体偶联药物的一部分，由 EGFR 抑制剂 Gefitinib 和 ADC linker MC-Sq-Cit-PAB 连接而成。

MC-Sq-Cit-PAB-Gefitinib

MC-Sq-Cit-PAB-Gefitinib Chemical Structure

CAS No. : 1941168-63-3

规格 是否有货
100 mg   询价  
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生物活性

MC-Sq-Cit-PAB-Gefitinib is a drug-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.

IC50 & Target

Traditional Cytotoxic Agents

 

分子量

1000.53

Formula

C50H61ClFN10O9+
CAS 号

1941168-63-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.

    [2]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

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