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Boc-piperazine-benzoic acid
Boc-piperazine-benzoic acid 是一种 PROTAC linker,可用来合成 PROTAC,例如雄激素受体 (AR) 降解剂 ARD-2128 (HY-13229)。
Boc-piperazine-benzoic acid Chemical Structure
CAS No. : 162046-66-4
规格 | 价格 | 是否有货 | 数量 |
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500 mg | ¥400 | In-stock | |
1 g | ¥640 | In-stock | |
5 g | 询价 | ||
10 g | 询价 |
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生物活性 |
Boc-piperazine-benzoic acid is a PROTAC linker and can be used in the synthesis of PROTACs, such as PROTAC androgen receptor (AR) degrader ARD-2128 (HY-13229)[1]. |
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体外研究 (In Vitro) |
ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. ARD-2128 has the potential for the research of the prostate cancer[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
306.36 |
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Formula |
C16H22N2O4 |
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CAS 号 |
162046-66-4 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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参考文献 |
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