PPC-NHS ester(Synonyms: 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate)

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PPC-NHS ester (Synonyms: 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate)

PPC-NHS ester 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。

PPC-NHS ester(Synonyms: 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate)

PPC-NHS ester Chemical Structure

CAS No. : 107348-47-0

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100 mg ¥4600 In-stock
1 g ¥22990 询价
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生物活性

PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

326.39

Formula

C13H14N2O4S2

CAS 号

107348-47-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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