NH2-MPAA-NODA

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NH2-MPAA-NODA 

NH2-MPAA-NODA 是一种基于硝基的可光裂解的 linker,它有一个 NODA 修饰单元和一个 MPAA 主链。NH2-MPAA-NODA 可以通过标记 18F-氟化物来用作放射性标签。

NH2-MPAA-NODA

NH2-MPAA-NODA Chemical Structure

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5 mg ¥3500 询问价格 & 货期
10 mg ¥5500 询问价格 & 货期
50 mg ¥16500 询问价格 & 货期

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生物活性

NH2-MPAA-NODA is a nitroveratryl-based photocleavable linker, it has a NODA motif and a methyl phenyl acetic acid (MPAA) backbone[1]. NH2-MPAA-NODA can be used as a radiolabel by labeling with 18F-fluoride.

IC50 & Target

IC50: Nitroveratryl-based photocleavable linker

体外研究
(In Vitro)

NH2-MPAA-NODA contains the 1,4,7-triazacyclononane-1,4-diacetate (NODA) motif with a methyl phenyl acetic acid (MPAA) backbone, and it has enough ability to form stable Al18F-chelates. The organ of luoroaluminates are easily accessible from the reaction of 1 and AlF3.
NH2-MPAA-NODA can be conjugated to some inhibitors/antagonists labeled with 18F for PET imaging of targeting tumors. It also can be used as a radiolabel of peptides[1]

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

435.52

Formula

C21H33N5O5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

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