Hydroxy-PEG4-(CH2)2-Boc

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Hydroxy-PEG4-(CH2)2-Boc 

Hydroxy-PEG4-(CH2)2-Boc 是一种用于合成抗体偶联药物 (ADC) 的 ADC linker，Hydroxy-PEG4-(CH2)2-Boc 源于专利WO2004008101A2 (化合物 191)。Hydroxy-PEG4-(CH2)2-Boc 也可用作 PROTAC linker 用于 PROTAC 的合成。.

Hydroxy-PEG4-(CH2)2-Boc

Hydroxy-PEG4-(CH2)2-Boc Chemical Structure

CAS No. : 518044-32-1

规格 价格 是否有货 数量
500 mg ￥1650 In-stock
1 g   询价  
5 g   询价  

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生物活性

Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target

Non-cleavable

 

Alkyl/ether

 

PEGs

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

322.39

Formula

C15H30O7
CAS 号

518044-32-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2.

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