Propargyl-PEG4-amine

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Propargyl-PEG4-amine 

Propargyl-PEG4-amine 是一种 PROTAC linker，属于 PEG 类。Propargyl-PEG4-NH2 可用于合成一系列 PROTAC 分子。

Propargyl-PEG4-amine

Propargyl-PEG4-amine Chemical Structure

CAS No. : 1013921-36-2

规格 价格 是否有货 数量
25 mg ￥500 In-stock
50 mg ￥800 In-stock
100 mg ￥1100 In-stock
200 mg   询价  
500 mg   询价  

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生物活性

Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

231.29

Formula

C11H21NO4
CAS 号

1013921-36-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Banerjee SR, et al. 111In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific MembraneAntigen-Expressing Tissues. Biomacromolecules. 2017 Jan 9;18(1):201-209.

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