Silybin B(Synonyms: 水飞蓟宾B)

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Silybin B (Synonyms: 水飞蓟宾B) 纯度: ≥99.0%

Silybin B 是从 Silybum marianum 中分离出的一种黄酮木脂素,具有抗肿瘤活性。Silybin B 是水飞蓟素最有效的抗纤维原性和抗低聚物成分,是一种有前景的抗阿尔茨海默病药物候选。

Silybin B(Synonyms: 水飞蓟宾B)

Silybin B Chemical Structure

CAS No. : 142797-34-0

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生物活性

Silybin B, a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease drug candidate[1][2].

分子量

482.44

Formula

C25H22O10

CAS 号

142797-34-0

中文名称

水飞蓟宾B

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738.

    [2]. Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.

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