2′-Deoxypseudoisocytidine

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2′-Deoxypseudoisocytidine 

2′-Deoxypseudoisocytidine 是一个核苷类似物。

2

2′-Deoxypseudoisocytidine Chemical Structure

CAS No. : 65358-18-1

规格 价格 是否有货
10 mM * 1 mL in DMSO ￥4749 询问价格 & 货期
5 mg ￥6500 询问价格 & 货期
10 mg ￥9500 询问价格 & 货期
25 mg ￥19500 询问价格 & 货期
50 mg ￥29500 询问价格 & 货期
100 mg ￥47000 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

2′-Deoxypseudoisocytidine is a nucleoside analogue.

体外研究
(In Vitro)

2′-Deoxypseudoisocytidine is a modified base which can be used as a allele-specific blocker probe to discriminate sequence variation between different alleles and quantitate rare (e.g., mutant) allelic variants, such as SNPs, or nucleotide (NT) insertions or deletions, in samples comprising abundant allelic variants with high specificity and selectivity[1]. 2′-Deoxypseudoisocytidine (2′d‐PIC) and its analogues are also used as novel base-pairing agents in oligonucleotides to investigate DNA and RNA structures and functions[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

227.22

Formula

C9H13N3O4
CAS 号

65358-18-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
In Vitro: 

DMSO : ≥ 106.5 mg/mL (468.71 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.4010 mL 22.0051 mL 44.0102 mL
5 mM 0.8802 mL 4.4010 mL 8.8020 mL
10 mM 0.4401 mL 2.2005 mL 4.4010 mL

参考文献

  • [1]. Caifu Chen, et al. Methods, Compositions, and Kits for Detecting Allelic Variants. US 20100285478 A1.

    [2]. Serpi M, et al. Synthetic Approaches for the Preparation of Phosphoramidate Prodrugs of 2′-Deoxypseudoisocytidine. ChemistryOpen. 2017 May 5;6(3):424-436.

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