PNU-159682 carboxylic acid

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PNU-159682 carboxylic acid 

PNU-159682 carboxylic acid (compound 53) 是一种有效的 ADC 细胞毒素,编码 C 型凝集素/C 型凝集素样结构域 (CTL/CTLD) 超家族的成员。PNU-159682 carboxylic acid 具有蛋白质折叠和多种功能,例如细胞粘附,细胞信号传导,糖蛋白更新以及在炎症和免疫反应中的作用。

PNU-159682 carboxylic acid

PNU-159682 carboxylic acid Chemical Structure

CAS No. : 1204819-92-0

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生物活性

PNU-159682 carboxylic acid (compound 53) is a potent ADCs cytotoxin and encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. PNU-159682 carboxylic acid has protein fold and diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response[1].

IC50 & Target[1]

Daunorubicins/Doxorubicins

 

分子量

627.59

Formula

C31H33NO13

CAS 号

1204819-92-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1.

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