Tubulin polymerization-IN-3

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Tubulin polymerization-IN-3 

Tubulin polymerization-IN-3 (化合物 4c) 是一种有效的微管蛋白聚合抑制剂，IC50 值为 3.84 µM。Tubulin polymerization-IN-3 可诱导结肠癌细胞凋亡。

Tubulin polymerization-IN-3

Tubulin polymerization-IN-3 Chemical Structure

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生物活性

Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC50 of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells[1].

分子量

413.86

Formula

C20H20ClN5O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Mohamed HS, et, al. Design, synthesis, biological assessment, and in-Silico studies of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors. Bioorg Chem. 2022 Apr;121:105687.

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