VEGFR-2-IN-16

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

VEGFR-2-IN-16 

VEGFR-2-IN-16 (Compound 15b) 是一种有效的 VEGFR-2 抑制剂，IC50 值为 86.36 nM。VEGFR-2-IN-16 具有抗肿瘤活性。

VEGFR-2-IN-16

VEGFR-2-IN-16 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

VEGFR-2-IN-16 (Compound 15b) is a potent VEGFR-2 inhibitor with an IC50 of 86.36 nM. VEGFR-2-IN-16 shows antitumor activities[1].

IC50 & Target

VEGFR2

86.36 nM (IC50)

体外研究
(In Vitro)

VEGFR-2-IN-16 (Compound 15b) shows antiproliferative activities with IC50 values of 17.39 ± 1.54, 25.58 ± 2.31, 19.88 ± 1.79 and 233.21 ± 2.39 µM against HepG2, PC3, MCF-7 and WI-38 cells, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

410.25

Formula

C21H13Cl2N3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Abdallah AE, et al. Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors. J Enzyme Inhib Med Chem. 2022 Dec;37(1):573-591.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务